First-in-Human (FIH) Trial
This is the very first time a drug is given to people — never humans before, only animals (and cell cultures). It's essentially Phase 1a. The goals are: 1. Safety — does the drug cause unexpected side...
Explainers tagged “Safety”
Phase 1a/b Clinical Trial
What the phases mean:Phase 1a: First-in-human testing. The primary goal is safety: "Is this drug safe in humans at all?" A small group of patients receives escalating doses to find the maximum tolerat...